abstract：BACKGROUND AND PURPOSE:Cardiac troponins have shown to be specific markers of myocardial injury. The aim of this prospective study was to compare patterns and kinetics of troponin I and T after coronary artery bypass grafting (CABG) with or without perioperative myocardial infarction (PMI). PATIENTS AND METHODS:119 pa...

journal_title：Herz

authors： Peivandi AA,Dahm M,Opfermann UT,Peetz D,Doerr F,Loos A,Oelert H

更新日期：2004-11-01 00:00:00

abstract：:As a result of an aging, increasingly obese, and decreasingly physically active population, the global incidence and prevalence of type 2 diabetes mellitus (DM) is increasing. While little can be done to influence the contribution of aging to the increasing global prevalence of diabetes, opportunities abound to develo...

journal_title：Herz

authors： Berry J,Keebler ME,McGuire DK

更新日期：2004-08-01 00:00:00

abstract：:Diabetes mellitus is an increasingly prevalent condition in the modern era. Coronary artery disease is the major cause of mortality in this population. Despite advances in the therapeutic modalities available for management of coronary artery disease, diabetic patients tend to have worse short and long term outcomes. ...

journal_title：Herz

authors： John JM,Bhatt DL

更新日期：2004-08-01 00:00:00

abstract：:Diving with self-contained underwater breathing apparatus (scuba) has become a popular recreational sports activity throughout the world. A high prevalence of cardiovascular disorders among the population makes it therefore likely that subjects suffering from cardiovascular problems may want to start scuba diving. Alt...

journal_title：Herz

authors： Muth CM,Tetzlaff K

更新日期：2004-06-01 00:00:00

abstract：:Blood pressure, together with proteinuria, represents one of the most important factors in the progression of chronic renal failure (CRF). Antihypertensive therapy is beneficial to slow down the progression of a variety of chronic renal diseases, no matter what the cause. Intraglomerular hypertension, increased glomer...

journal_title：Herz

authors： Wolf S,Risler T

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The endothelial lining is a confluent monolayer of thin and rhomboid-shaped cells, that covers the inner surface of all blood vessels. However, the essential role of endothelial cells in all aspects of cardiovascular physiology, homeostasis and the pathogenesis of most cardiovascular diseases no ...

journal_title：Herz

authors： Wilhelmi M,Leyh R,Haverich A

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:To determine predictors of patient radiation exposure due to percutaneous coronary interventions (PCI) and to compare our results with the "preliminary reference levels", recently proposed by the European DIMOND research cardiology group: i. e., 75 Gy.cm(2) for dose area kerma product (DAP), 17 min for fluorosc...

journal_title：Herz

authors： Kuon E,Empen K,Rohde D,Dahm JB

更新日期：2004-03-01 00:00:00

abstract：:Coronary stent implantation is currently performed in > 80% of percutaneous coronary interventions. Its main late complication is the development of in-stent restenosis (ISR), occurring in 10-80% of lesions treated in daily practice. The classification by Mehran et al. is most commonly used. Current therapeutic option...

journal_title：Herz

authors： Ong AT,Aoki J,McFadden EP,Serruys PW

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:This article describes the potential of dynamic contrast- enhanced magnetic resonance tomography (DCE-MRT) for the visualization and quantification of blood flow of lower leg muscles at rest and after individually adjusted muscular exercise. PATIENTS AND METHODS:Five cases were chosen to exemplify the qualitat...

journal_title：Herz

authors： Leppek R,Hoos O,Sattler A,Kohle S,Azzam S,Al Haffar I,Keil B,Ricken P,Klose KJ,Alfke H

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have found an association between overweight and increased mortality arising primarily from cardiovascular disorders. A major determinant is a chronically raised sympathetic nervous system activity which can arise from calorie intake-dependent and -independent mechanisms. Calorie-depend...

journal_title：Herz

authors： Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In experimental arterial hypertension, left ventricular hypertrophy (LVH) becomes pathologic with impaired myocardial function if myocardial fibrosis occurs. Myocardial fibrosis is associated with activated circulating or local renin-angiotensin-aldosterone systems. The primary objective of this ...

journal_title：Herz

authors： Brilla CG,Rupp H,Maisch B

更新日期：2003-12-01 00:00:00

abstract：:Catheter ablation for ventricular fibrillation in structurally normal hearts is in its infancy. Recently, catheter ablation of idiopathic ventricular fibrillation as well as ventricular fibrillation associated with the long QT and Brugada syndromes has been described. This review article is a summary of our current un...

journal_title：Herz

authors： Weerasooriya R,Hsu LF,Scavée C,Sanders P,Hocini M,Cabrera JA,Horlitz M,Schley P,Guelker H,Jaïs P,Haïssaguerre M

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:It is believed that most myocardial infarctions result from the rupture of "vulnerable plaques", that share certain common characteristics. These plaques typically consist of a lipid-rich core in the central portion of the thickened intima, covered by a thin friable fibrous cap. Today, one of the important c...

journal_title：Herz

authors： Gerckens U,Buellesfeld L,McNamara E,Grube E

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Short-term prognosis of patients with chest pain and angiographically smooth coronary arteries is good in terms of development of coronary events (fatal or nonfatal myocardial infarction, coronary death, new coronary heart disease), but long-term studies are rare. PATIENTS AND METHODS:185 consecutive patien...

journal_title：Herz

authors： Scholz M,Wegener K,Unverdorben M,Klepzig H

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:In Germany, about 6,000 pregnancies in women with grown-up congenital heart disease or acquired valvular lesions are expected per year. The pregnancy-related physiology is characterized by a 50% increase in plasma volume and a 25% increase in erythrocyte volume. The cardiac output increases by 40% due to 30%...

journal_title：Herz

authors： Horstkotte D,Fassbender D,Piper C

更新日期：2003-05-01 00:00:00

abstract：INTRODUCTION:One crucial goal of magnetic resonance imaging (MRI) in patients with coronary artery disease (CAD) is the characterization of myocardial microcirculation that reflects tissue supply much better than detection and quantification of a stenosis itself. PERFUSION: Myocardial perfusion is one important paramet...

journal_title：Herz

authors： Wacker CM,Bauer WR

更新日期：2003-03-01 00:00:00

abstract：OBJECTS:To show all cardiac evaluations multislice computed tomography (MSCT) can perform. METHODS:MSCTs were performed on an MSCT scanner (Mx8000; Philips Medical Systems) with enhanced contrast acquisition. The reconstructed images were sent to a workstation for multiplanar reconstruction, volume rendering, and 3-D ...

journal_title：Herz

authors： Carrascosa PM,Capuñay CM,Parodi JC,Padilla LT,Johnson P,Carrascosa JM,Chandra S,Smith D,Belardi J

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Inherited ventricular arrhythmias such as the long QT syndrome (LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), idiopathic ventricular fibrillation (VF), and arrhythmogenic right ventricular cardiomyopathy (ARVC) account for a relevant proportion of sudden cardiac death...

journal_title：Herz

authors： Wichter T,Schulze-Bahr E,Eckardt L,Paul M,Levkau B,Meyborg M,Schäfers M,Haverkamp W,Breithardt G

更新日期：2002-12-01 00:00:00

abstract：CASE REPORT:A 41-year-old male saw his general practitioner because of progressive atypical angina symptoms and palpitations for the last 7 years. Chest X-ray showed a mediastinal mass. Further investigation by computed tomography (CT), magnetic resonance imaging (MRI) and cardiac catheterization revealed two bronchoge...

journal_title：Herz

authors： Kusch B,Vogt S,Rybinski L,Moosdorf R

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that circulating progenitor cells contribute to the formation of new blood vessels in adults after tissue ischemia. The infusion of these progenitor cells was used as a therapeutic approach to increase vascularization. In several animal models, progenitor cells improved vascularization...

journal_title：Herz

authors： Walter DH,Dimmeler S

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The beta-adrenergic receptors of the myocardium play an important role in the regulation of heart function. The beta-adrenergic receptors belong to the family of G-protein coupled receptors. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors). The receptors consist of seven membr...

journal_title：Herz

authors： Wallukat G

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Modern high-resolution imaging techniques have provided new insights into the pathogenesis of aortic dissection during recent years. Distinct pathologic entities or potential precursors of classic false-lumen aortic dissection such as intramural hematoma or penetrating atherosclerotic ulcer have been identif...

journal_title：Herz

authors： Eggebrecht H,Baumgart D,Herold U,Piotrowski J,Barkhausen J,Wiesemes R,Peters J,Rühm SG,Jakob H,Erbel R

更新日期：2002-09-01 00:00:00

abstract：:Regardless the general acceptance of cardiac operations by physicians and patients as routine procedures since the early seventies conventional cardiac surgery is still associated with a significant surgical trauma and exceptional invasiveness in part effected by the extracorporeal circulation. In parallel to the comm...

journal_title：Herz

authors： Cremer J,Böning A,Fraund S

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Although several classical studies seemed to provide clear ideas on the pathophysiology of atrial fibrillation, current concepts have to be modified on the basis of more recent findings. REENTRANT CIRCUITS:Based on the findings of Garrey and of Moe & Abildskov, atrial fibrillation has long been considered a...

journal_title：Herz

authors： Schoels W,Bauer A,Becker R,Senges JC,Voss F

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Contrast echocardiography has been used as a clinical method for more than 20 years. Using conventional ultrasound techniques the clinical use of contrast was limited. Now the development of "contrast specific" imaging modalities has increased the indications for contrast echocardiography. CONTRAST AGENTS:F...

journal_title：Herz

authors： Becher H

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Once contraindicated, beta-blockers have become an established, evidence-based, recommended treatment concept in chronic heart failure during the last years. PATHOPHYSIOLOGY:The increased activation of the adrenergic system in heart failure syndrome, which leads to transmission of several adverse biological...

journal_title：Herz

authors： Hoffman J,Grimm W,Maisch B

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:There is an increasing prevalence of older adults (> 65 years) with hypertension and the need for antihypertensive medication. It is well established that elderly hypertensive patients benefit from drug treatment with regards to cardiovascular morbidity and mortality. Due to the comorbidity and reduced quali...

journal_title：Herz

authors： Michalsen A,Wenzel RR,Mayer C,Broer M,Philipp T,Dobos GJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Culture-negative endocarditis is a diagnostic challenge with variable clinical presentation and protean manifestations. ETIOLOGY AND DIAGNOSIS:The two main causes why endocarditis may be culture-negative are 1. antibiotic treatment prior to obtaining blood cultures, and 2. the presence of fastidious microor...

journal_title：Herz

authors： Kupferwasser LI,Bayer AS

更新日期：2001-09-01 00:00:00

abstract：IMPORTANCE:Anxiety and depression are frequent problems in patients with heart diseases. Prevalences vary between 15 and 50%, depending on diagnostic criteria as well as on sociodemographic and medical patient characteristics. During the last 10-15 years, a large number of studies have shown that anxiety and depression...

journal_title：Herz

authors： Herrmann-Lingen C

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:The progression of coronary atherosclerosis is determined by risk factor exposure. It is also an important predictor of future cardiac events in its own right. Coronary calcium represents an integral part of coronary atherosclerosis. Accurate measurements can be obtained by using electron-beam computed tomog...

journal_title：Herz

authors： Schmermund A

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The current epidemic of obesity is primarily a consequence of the modern lifestyle characterized by a hypercaloric, high-fat diet and lack of physical activity. INTEGRATED TREATMENT CONCEPT:In order to establish a treatment strategy oriented at the pathogenesis of the disorder it is necessary to strive for ...

journal_title：Herz

authors： Hauner H

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:INFLAMMATORY PROCESS: Within the vessel wall is considered to be crucial for initiation and progression of atherosclerosis. As response to endothelial injury a focal inflammatory response arises which can lead to plaque vulnerability and rupture and a consecutive acute coronary syndrome. Systemic markers of ...

journal_title：Herz

authors： Blankenberg S,Rupprecht HJ,Bickel C,Hafner G,Meyer J

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Unstable angina accounts for more than one million hospital admissions annually. 6-8% of patients with this condition have non-fatal myocardial infarction or die within the first year after diagnosis. Recently, the term "acute coronary syndromes" has been used to describe the spectrum of conditions that incl...

journal_title：Herz

authors： Auer J,Berent R,Maurer E,Mayr H,Weber T,Eber B

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The treatment of concomitant atrial tachyarrhythmias in patients with malignant ventricular tachyarrhythmias is a major challenge for new defibrillator devices. Atrial fibrillation is not only responsible for inappropriate ventricular therapies, but also reduced left ventricular performance, especially in pa...

journal_title：Herz

authors： Wolpert C,Jung W,Herwig S,Schimpf R,Lüderitz B

更新日期：2001-02-01 00:00:00

abstract：:It is still controversial whether the arrhythmias in acute pericarditis are of myocardial or pericardial origin. The aim of the present study was to investigate the occurrence of arrhythmias and conduction disorders in patients with acute pericarditis with no endomyocardial biopsy evidence of myocarditis (group 1: 40 ...

journal_title：Herz

authors： Ristić AD,Maisch B,Hufnagel G,Seferovic PM,Pankuweit S,Ostojic M,Moll R,Olsen E

更新日期：2000-12-01 00:00:00

abstract：:A congenital aneurysm of the ductus arteriosus Botalli was detected by chest X-ray as an intrathoracic mass in a 7-day-old infant. Following confirmation of the diagnosis by echocardiography and MRI the aneurysm was successfully resected via left lateral thoracotomy without cardiopulmonary bypass. The postoperative co...

journal_title：Herz

authors： Peivandi AA,von Bülow S,Schmid FX,Kampmann C,Choi YH,Oelert H

更新日期：2000-11-01 00:00:00

abstract：:Coronary artery disease is still the no. 1 killer in the developed countries and must thus be detected and treated at an earlier stage. If coronary artery disease is advanced, patients have to be examined regarding the need for revascularization. For secondary prevention, of course, an optimal change of life style and...

journal_title：Herz

authors： Silber S,Krischke I,Prohaska M

更新日期：2000-09-01 00:00:00

abstract：:A Monte Carlo simulation model is presented which allows an assessment of the costs for coronary heart disease (CHD) (from a social security perspective) to be made over a time interval of 10 years. The difference between a CHD population and a normal population is calculated whereby the CHD population corresponds in ...

journal_title：Herz

authors： Hinzpeter B,Klever-Deichert G,Wendland G,Lauterbach KW

更新日期：2000-08-01 00:00:00

abstract：:MR with its various imaging protocols including spin-echo MR-imaging, gradient MR imaging, flow-mapping and MR angiography is the ideal tool for noninvasive assessment of any kind of aortic diseases. The technique allows to image the aorta both in the thoracic cage and in the abdominal aspects better than any other to...

journal_title：Herz

authors： Nienaber CA,Fattori R

更新日期：2000-06-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) has a number of characteristics which make it attractive for guidance of intravascular therapeutic procedures, including high soft tissue contrast, imaging in any arbitrary oblique plane, lack of ionizing radiation, and the ability to provide functional information, such as flow veloci...

journal_title：Herz

authors： Ladd ME,Debatin JF

更新日期：2000-06-01 00:00:00